Pseudomembranous colitis during antibiotic therapy
نویسندگان
چکیده
منابع مشابه
Roentgenographic features in antibiotic-associated pseudomembranous colitis.
CASE PRESENTATIONS Case 1 . A 62-year-old woman with diabetes was admitted because of an infected toe. Physical examination was normal except for an ulceration of the left 4th toe. Routine laboratory studies revealed only elevated blood sugar and moderate ketonuria. A roentgenogram of the toe revealed osteomyelitis. The infection improved with clindamycin therapy (300 mg IV, t:d), and the toe w...
متن کاملPseudomembranous colitis
In 1978, C. difficile was identified as the causative agent of pseudomembranous colitis [1]. There has been a worldwide increase in the incidence and severity of C. difficile-associated diarrhea (CDAD) due to increased use of broad-spectrum antimicrobial, crowded hospital wards [2,3] and/or poor infection control [4,5]. Pseudomembranous colitis associated with antibiotic use may alter the balan...
متن کاملPseudomembranous Colitis
PMC has emerged, particularly in recent years, as a major and very expensive healthcare problem. Spores formed by the organism are implicated in spread of infection and have implications for hygiene and prevention of infection. C. difficile is an anaerobic Gram-positive rod which secretes two types of toxin (A and B), which cause disruption to the barrier function of the colonic mucosa. They ar...
متن کاملFaecal toxin and severity of antibiotic-associated pseudomembranous colitis.
The relationship between faecal toxin titre, histological evidence of pseudomembrane in the rectum, and severity of antibiotic-associated colitis has been analysed from data on 62 patients whose faeces contained Clostridium difficile toxin. There was a significant correlation between a toxin titre of 6400 or more and the presence of pseudomembrane (p less than 005). There was no correlation bet...
متن کاملPseudomembranous colitis associated with antibiotic prophylaxis in orthopaedic surgery.
We report 16 orthopaedic patients who had antibiotic-associated diarrhoea (pseudomembranous colitis) after operation. There was an association with the use of cephradine and with the prolongation of prophylaxis for more than three peri-operative doses. Five cases occurred as a cluster, suggesting that the causative agent, Clostridium difficile, may be infectious in some situations.
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ژورنال
عنوان ژورنال: Medicinski pregled
سال: 2003
ISSN: 0025-8105,1820-7383
DOI: 10.2298/mpns0308381c